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What are wrinkles? How can LDN be used to treat it? by Benjamin Moser

Wrinkle Solutions are fine and deep lines that form on the skin, usually on the parts that are exposed to the sun such as the face, arms, neck, hands, etc According to Benjamin Moser. It is quite a natural part of aging. Despite genetics, mainly determining skin structure and texture, sun exposure is a major cause of wrinkles especially for people with light skin. Pollutants and smoking also contribute to wrinkling.

If your wrinkles bother you, you have more options than ever to help smooth them or make them less visible. Medications, skin-resurfacing techniques, fillers, and surgery top the list of effective wrinkle treatments.

What do wrinkles look like?

Wrinkles are in the form of fine lines and deep creases in the skin. Sometimes wrinkles may form very deep cracks or grooves that are more noticeable in areas like around the mouth, eyes, and neck.

What causes wrinkles?

Multiple factors can cause wrinkles. Some of them are manageable, while others cannot be dealt with. Below are a few causes of wrinkles:


Age is the significant most factor that causes wrinkles. As you age, it’s quite natural that your skin becomes loose and fragile. It loses its elasticity because of the decreased production of natural oils by the body, and the reduction of fat in the layers of skin. This makes skin look wrinkled, saggy, and old.

Exposure to ultraviolet (UV) light.

After age, the second most significant cause of wrinkles is the long-time exposure to ultraviolet (UV) radiation. It causes the natural aging process to speed up at an early age. The direct radiations from the sun cause the connective tissue in the skin to break down. The connective tissue is made up of collagen and elastin that is present in the deeper layers of the skin. The loss of connective tissue results in the loss of skin strength and flexibility. Your skin will start to appear saggier and the wrinkles become more obvious

Hormonal changes

As you grow in age, you experience hormonal changes. It’s a natural part of life. In women, the levels of estrogen and progesterone decrease significantly. These hormones are responsible for maintaining the health of the skin along with the female sexual health. Moreover, the productions of collagen get reduced. All of this results in dried, loose, saggy, and extremely dehydrated skin. Due to this, the wrinkles start forming.


The habit of smoking is likely to speed up the natural process of skin aging and hence causing wrinkles. This happens due to tobacco’s ability to cut down on collagen.

Repeated facial movements

Your continuous facial gestures, movements, and expressions can result in the appearance of fine and deep lines in the form of wrinkles According to Benjamin Moser.  Such facial expressions include smiling, furrowing, or squinting, etc. Every time you make an expression, the muscles in your skin for a groove beneath your skin. And then with time the skin loses its flexibility and is no longer able to come back in its place. The grooves become a permanent part of your face.

When should you see a doctor?

You can see a doctor if you’re conscious about how your skin looks. Your doctor or dermatologist will examine your skin so that he or she can make a personalized prescription for you. The doctor is most likely to recommend some treatments, medications, and even lifestyle changes to reduce your wrinkles.

If you are in search of a good doctor in town, you can contact the harbor compounding pharmacy. Here, we have a list of highly qualified doctors who are on board with us. They have a solution to every kind of health problem of yours.

What are the available methods to treat wrinkles?

There are several options available to you for reducing the appearance of your wrinkles or helping to smooth them. These methods include surgeries, medications, and other non-surgical methods.

The medications that can be used to treat wrinkles include topical retinoids, nonprescription wrinkles creams, anti-aging creams, Low Dose Naltrexone (LDN), Hormone Replacement Therapy (HRT), etc. Other methods that can be used are laser resurfacing, face lifting, chemical peel, photodynamic rejuvenation, dermabrasion, botox, microdermabrasion, soft tissue fillers, etc.

Role of compounding pharmacies in providing Low Dose Naltrexone

The FDA has not yet approved the use of low-dose naltrexone for any condition other than drug addiction, including opioid abuse and alcoholism. However, in lower doses, this medicine could benefit patients undergoing many complex medical conditions.

Because LDN is not approved by FDA for off-label treatments, the only way to take naltrexone in lower doses is by getting your prescription filled by a compounding pharmacy such as Harbor Compounding Pharmacy. Compounding pharmacies work uniquely from standard pharmacies. They develop or compound drugs intended to meet your particular needs.

For instance, if your doctor prescribed you 2mg of low-dose naltrexone, services of a compounding pharmacy would be needed to create that particular dose of the medication, as naltrexone is usually available in 50 mg tablets only. Also, if you are incapable of taking tablets orally, different options may be provided to you.

The Harbor Compounding Pharmacy will able to compound your LDN into eye drops, sublingual drops, topical lotions, creams, or even liquid dosage forms. The price can range, depending on the dosage form of your low-dose naltrexone. You can chat with your compounding pharmacist to decide which one form of administration suits you the best.

High levels of cortisol

Cortisol is a stress hormone that is produced by the adrenal glands. Osteoporosis due to high levels of cortisol in the blood is quite uncommon, but not impossible. High levels of cortisol are commonly known to cause obesity and weight gain, but it also causes weaker bones.

In sex therapy sometimes, women are too embarrassed to share their sexual problems with their partners. So, issues can be dealt with a help of sex therapy, which is performed by specialized sex therapists. They provide sex therapy to couples which may help to ease the concerns and disputes between the couples. Furthermore, a sex specialist or therapist may provide you and your partner with sex education which will help both of you to understand each other’s bodies in a better way.  So It will help to enhance your body’s sexual response to sexual activities so, intimacy with your partner.
Change your medications you are taking antidepressants because any such medications that have effects on libido and sexual desire, you must talk to your doctor about it. It is possible, additionally, the cause of dysorgasmia lies in the use of these medications.

Treating wrinkles with Low Dose Naltrexone (LDN) and Hormone Replacement Therapy (HRT)

Low Dose Naltrexone (LDN) is not hidden for the wonders it does. It has chemicals that help to reduce the appearance of wrinkles and make skin look fresher and healthier. People who have taken LDN for treating their wrinkles have shown a significant improvement. The depth of wrinkles was seen to have decreased, causing the skin to appear much better.

Hormone replacement therapy (HRT) can be given to people who are experiencing wrinkles to hormonal changes in the body. It can help to maintain the levels of hormones in the body, such as estrogen and progesterone. As mentioned earlier, these hormones are vital for skin health and strength.

Harbor Compounding Pharmacy

Low Dose Naltrexone (LDN) and Hormone Replacement Therapy (HRT) are available at the harbor compounding pharmacy. Do not hesitate to contact their website for more details regarding the drug or your condition.


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